Endocrine Abstracts

Disturbances of thyroid hormones produce clinical symptoms but hormonal level at which this happens vary from patient to patient. In order to determine how much hormonal change patients can tolerate before developing symptoms we retrospectively collected data of 86 hyperthyroid and 48 hypothyroid patients, 120 females and 14 males aged 28–85 and 23–74 yrs respectively. We included only patients who at some time during treatment had abnormal values of TSH and/or thyro...

Level of pituitary trophic hormone dictates dose of hormone replacement (HRT) in endocrine gland hypofunction. We examined 28 women receiving HRT in postmenopausis aged 46–63 yrs (54±4.27 yrs). In average patients started HRT two years after last spontaneous menstrual bleeding (28±3.76 months, 1–132 months). 8 patients used transdermal estradiol, 10 peroral combination of estradiol, estriol and norethisterone and 10 patients were treated by fixed peroral co...